2012(10)

43. 炭素‒水素結合直接変換をとする生物活性物質の合成-直感的に分子をつなげる新手法
2016-09-19_17-14-34 2016-09-19_17-18-44

Yamaguchi, J.*
化学と工業 2012, 65, 952.


42. Pd-catalyzed direct C–H bond functionalization of spirocyclic sigma-1 ligands: generation of a pharmacophore model and analysis of reverse binding mode by docking into a 3D homology model of the sigma-1 receptor

2016-09-19_17-13-14 jm-2012-00894h_0016

Meyer, C.; Schepmann, D.; Yanagisawa, S.; Yamaguchi, J.; Dal Col, V.; Laurini, E.; Itami, K.*; Pricl, S.; Wünsch, B.*
J, Med. Chem. 201255, 8047–8065.
DOI:10.1021/jm300894h


41. Decarbonylative C–H Coupling of Azoles and Aryl Esters: Unprecedented Nickel Catalysis and Application to the Synthesis of Muscoride A

2016-09-19_17-12-15 ja-2012-06062c_0009

Amaike, K.; Muto, K.; Yamaguchi, J.*; Itami, K.*
J. Am. Chem. Soc.2012134, 13573–13576.
DOI:10.1021/ja306062c
Highlights Newspapers (Chu-nichi, Asahi, The Chemical Daily, Yahoo!News, Mynavi-News, Nikkan kogyo, Kagaku Shinbun), Most Read Articles in August 2012


40. Late-Stage C–H Bond Arylation of Spirocyclic sigma-1 Ligands for Analysis of Complementary sigma-1 Receptor Surface”

2016-09-19_17-06-31 mfig000

Meyer, C.; Schepmann, D.; Yanagisawa, S.; Yamaguchi, J.; Wünsch, B.; Itami, K.*
Eur. J. Org. Chem. 2012, 5972–5979.
DOI:10.1002/ejoc.201200837


39. Synthesis of Bioactive Compounds through C–H Bond Functionalization”

2016-09-19_17-04-44 2016-09-19_17-05-43

Yamaguchi, J.*; Itami, K.*
Fine Chemicals 2012, 41, 38­–44.
[LINK]


38. Pd- and Cu-catalyzed C–H Arylation of Indazoles”

2016-09-19_17-03-32 1-s2.0-S0040402012008095-fx1

Hattori, K.; Yamaguchi, K.; Yamaguchi, J.*; Itami, K.*
Tetrahedron (Special Issue) 2012, 68, 7605–7612.
DOI:10.1016/j.tet.2012.05.091


37. Hindered Biaryls by C–H Coupling: Bisoxazoline-Pd Catalysis Leading to Enantioselective C-H Coupling”

2016-09-19_17-02-05 kazuya2012

Yamaguchi, K.; Yamaguchi, J.*; Studer, A.; Itami, K.*
Chem. Sci. 2012, 7, 2165–2169.
DOI:10.1039/C2SC20277H
Highlights RSC Chemical Science blog, Most Read Articles in March and April 2012


36. Mechanistic Studies on the Pd-catalyzed Direct C¿H Arylation of 2-Substituted Thiophene Derivatives with Arylpalladium Bipyridyl Complexes”

2016-09-19_17-01-19 mcontent-1

Steinmetz, M.; Ueda, K.; Grimme, S.; Yamaguchi, J.; Kirchberg, S.; Itami, K.*; Studer, A.*
Chem. Asian J. 2012, 7, 1256–1260.
DOI: 10.1002/asia.201101011


35. Nickel-Catalyzed C−H/C−O Coupling of Azoles with Phenol Derivatives”

2016-09-19_17-00-02 CO

Muto, K.; Yamaguchi, J.; Itami, K. *
J. Am. Chem. Soc. 2012134, 169–172.
DOI:10.1021/ja210249h
Highlights Newspapers (Yomiuri, Chu-nichi, The Chemical Daily, Yahoo!News, NanotechJapan Nikkan kogyo, Kagaku Shinbun), Most Read Articles (January, 2012), Highlighted as a “SynStory” article in SYNFORM (April 2012), Highlighted in Chemical Engineering (Feb 2012)


34. C–H Bond Functionalization: Emerging Synthetic Tools for the Synthesis of Natural Products and Pharmaceuticals”

2016-09-19_16-58-33 mcontent

Yamaguchi J.;* Yamaguchi, A. D.; Itami, K.*
Angew. Chem., Int. Ed­. 2012, 51, 8960–9009
DOI:10.1002/anie.201201666
Highlights Chemistry Views. Most Accessed Articles (2011–2013). Selected as the Cover of the Issue.

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